Scientists have made an unexpected discovery in the process of mitochondrial cell division. Mitochondria are cell structures that convert energy into forms that are usable by the cell. They are semi-autonomous in that they are only partially dependent on the cell to divide and grow. They have their own DNA, ribosomes, and can make their own proteins. According to scientists, it appears that another cell structure, the endoplasmic reticulum (ER), is associated with mitochondrial division. In the vast majority of instances, this division occurs at sites where the ER and mitochondria touch.
Research studies indicate that ER proteins assist in mitochondrial division by wrapping around and squeezing mitochondria. Another protein, dynamin related protein-1, subsequently assembles and tightens around the mitochondria causing them to divide. Information from the study not only reveals another function of ER in the cell, but may also have implications on our understanding of a number of diseases. Improperly functioning mitochondria have been associated with the development of diseases such as diabetes and cardiovascular disease.
Research studies indicate that ER proteins assist in mitochondrial division by wrapping around and squeezing mitochondria. Another protein, dynamin related protein-1, subsequently assembles and tightens around the mitochondria causing them to divide. Information from the study not only reveals another function of ER in the cell, but may also have implications on our understanding of a number of diseases. Improperly functioning mitochondria have been associated with the development of diseases such as diabetes and cardiovascular disease.
