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Understanding Science in Science Fictional Times



I just finished reading Rebecca Skloot's excellent book The Immortal Life of Henrietta Lacks. Lacks was a poor black tobacco farmer who was diagnosed with cervical cancer at the age of 30. Cells taken from her tumor were out to be the first human cells that could grow in the laboratory.

Those "immortal" cells - coded named HeLa - would play an a crucial role in testing the first effective polio vaccine developed by Jonas Salk in the mid-1950s. Since then, HeLa cells have been used in thousands of studies, and added to our understanding of how both normal and cancel cells function.

Skloot goes beyond discussing the science and bioethics surrounding the development of cell culture technology and human experimentation to provide a portrait of Henrietta as a person. And a big part of her story involves Skloot's decade-long interactions with Henrietta's family and friends, and in particular with Henrietta's daughter Deborah Lacks Pullum.

Deborah was a baby when Henrietta died from complications of cervical cancer in 1951. She never knew her mother, but really wanted to learn more. And even though she had little formal schooling, she wanted to know what was happening with her mother's cells. As Sklootdescribed it in an interview:
She had always wanted to know who her mother was but no one ever talked about Henrietta. So when Deborah found out that this part of her mother was still alive she became desperate to understand what that meant: Did it hurt her mother when scientists injected her cells with viruses and toxins? Had scientists cloned her mother? And could those cells help scientists tell her about her mother, like what her favorite color was and if she liked to dance.
Deborah began to teach herself about the basics of how cells work, and read everything she could about HeLa cells. But even when you have a solid background in biology, it can be hard to sort out what's solid science and what's speculation when scientific research is reported by the mainstream media. Even relatively mild headlines like "Cancer cells from long-dead woman invade other cultures" or "Human and plant cells combined" sound pretty sensational.

So it doesn't surprise me that while Deborah was struggling to understand all this unfamiliar information, she latched onto science fiction with related science. That all came bursting out during her first face-to-face meeting with Skloot:
"I saw [Jurassic Park] a bunch of times," she said. "They talking about the genes and taking them from cells to bring that dinosaur back to life and I'm like, Oh Lord, I got a paper on how they were doin that with my mother's cells too!" She held up another videocassette, this one a made-for-TV movie called The Clone. In it, an infertility doctor secretly harvest extra embryos from one of his patients and uses them to create a colony of clones of the woman's son, who died young in an accident.

"That doctor took cells from that woman and made them into little boys look just liker her child," Deborah told me. "That poor woman didn't even know about all the clones until she saw one walk out of a store. I don't know what I'd do if I saw one of my mother's clones walking around somewhere."